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Mevaldate reductase (NADPH) : ウィキペディア英語版
Mevaldate reductase (NADPH)

In enzymology, a mevaldate reductase (NADPH) () is an enzyme that catalyzes the chemical reaction
:(R)-mevalonate + NADP+ \rightleftharpoons mevaldate + NADPH + H+
Thus, the two substrates of this enzyme are (R)-mevalonate and NADP+, whereas its 3 products are mevaldate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-mevalonate:NADP+ oxidoreductase. Other names in common use include mevaldate (reduced nicotinamide adenine dinucleotide phosphate), reductase, and mevaldate reductase (NADPH).
==References==

* Wolstenholme, G.E.W. and O'Connor, M. (Eds.), ''CIBA Symposium on the Biosynthesis of Terpenes and Sterols'', London, 1959, p. 62–74.
* Jakoby, W.B. (Ed.), ''Enzymatic Basis of Detoxication'', vol. 1, Academic Press, New York, 1980, p. 249–260.


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